Related Experiment Videos
Effect of zinc deficiency on chromosomal abnormalities in mice
Y Ozkul1, N Dursun, A Erenmemişoğlu
1Department of Medical Biology, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
The Tohoku Journal of Experimental Medicine
|August 1, 1996
Abstract:
In the present study we investigated the effect of zinc-deficiency on chromosomal abnormalities and mitotic index, and the interaction of zinc-deficiency and methotrexate. Therefore, two zinc-deficient and two zinc-adequate diet received mouse groups were constituted. Methotrexate was injected to one of zinc-deficient and one of zinc-adequate diet groups. There were no structural and numerical abnormalities in all groups. However, mitotic index was significantly lower than other groups in zinc-deficient and methotrexate administered mice.