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Image-guided core biopsy in patients with breast disease
M J Chare1, C I Flowers, C J O'Brien
1Departments of Surgery, Neath General Hospital, UK.
The British Journal of Surgery
|October 1, 1996
Summary
Ultrasonographically-guided core biopsy aids breast cancer diagnosis, reducing surgical biopsies. This method accurately identifies malignancy and benign conditions, improving patient management.
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- Triple assessment is standard for breast lesions.
- Ultrasound-guided core biopsy (UGCB) is used when fine-needle aspiration cytology is inconclusive or for preferred diagnosis.
- UGCB serves as an adjunct to established diagnostic pathways.
Purpose of the Study:
- To evaluate the diagnostic utility and impact of UGCB in breast lesion assessment.
- To determine the effectiveness of UGCB in reducing the need for surgical biopsies.
- To assess the accuracy of UGCB in diagnosing both malignant and benign breast conditions.
Main Methods:
- Retrospective analysis of 2603 patients undergoing breast assessment.
- 143 patients underwent UGCB: 125 for initial diagnosis, 18 for histology in known malignancy.
- Data collected on diagnostic outcomes and subsequent surgical interventions.
Main Results:
- Malignancy diagnosed in 43 of 125 diagnostic UGCBs.
- 45 benign cases were managed non-surgically based on UGCB.
- 37 patients required surgical biopsy (13 malignant, 24 benign).
- Overall positive predictive value for malignancy was 98%.
Conclusions:
- Ultrasonographically-guided core biopsy is a valuable tool in breast lesion diagnosis.
- UGCB can significantly decrease the requirement for surgical biopsies for both benign and malignant breast conditions.
- High diagnostic accuracy supports the role of UGCB in optimizing patient management pathways.