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Related Experiment Videos

Access flow measured during hemodialysis

J Sands1, D Glidden, C Miranda

  • 1Renal Consultants of Wyoming Valley, P.C., Wilkes-Barre, Pennsylvania, USA.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|September 1, 1996
PubMed
Summary
This summary is machine-generated.

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Hemodialysis access flow, cardiac output, and mean arterial pressure modestly decrease during treatment. Further research is needed to determine if these changes impact access patency and thrombosis.

Area of Science:

  • Nephrology
  • Vascular Access
  • Hemodynamics

Background:

  • Adequate blood flow is crucial for hemodialysis efficacy and vascular access patency.
  • Access flow (QA) is not routinely monitored during hemodialysis sessions.
  • Understanding changes in QA during hemodialysis is essential for optimizing treatment and preventing complications.

Purpose of the Study:

  • To investigate whether hemodialysis access flow changes during treatment.
  • To identify factors that correlate with changes in access flow.
  • To assess the impact of hemodialysis on hemodynamic parameters.

Main Methods:

  • Hourly measurement of hemodialysis access flow using ultrasound dilution (QA-T) and duplex ultrasound with time-domain correlation (QA-S) in 19 patients.

Related Experiment Videos

  • Sequential measurement of mean arterial pressure (MAP) and cardiac output (CO) during hemodialysis.
  • Correlation analysis to determine relationships between QA, CO, and MAP.

    • Main Results:

    • Access flow remained unchanged by duplex ultrasound but decreased significantly by ultrasound dilution (132 ± 137 ml/m) by hour 4 (p < 0.05).
    • Cardiac output (586 ± 840 ml/m) and MAP (11.9 ± 13.0 mmHg) also decreased significantly during hemodialysis (p < 0.05 and p < 0.01, respectively).
    • Small positive correlations were observed between CO and QA (r = 0.32 for QA-T, r = 0.27 for QA-S; p < 0.05) and between CO and MAP (r = 0.35; p < 0.01).

    Conclusions:

    • Hemodialysis is associated with modest decreases in access flow, cardiac output, and mean arterial pressure.
    • Further studies are required to ascertain if access flow remains consistent outside of dialysis.
    • Investigating the utility of in-line access flow measurements may help reduce access thrombosis.