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Related Experiment Videos

A decrease in cardiovascular risk factors in healthy 40-year-old Swedish men between 1980-1983 and 1991-1992

P Tornvall1, P Båvenholm, M L Hellénius

  • 1Atherosclerosis Research Unit, King Gustaf V Research Institute, Karolinska Institute, Stockholm, Sweden.

Journal of Cardiovascular Risk
|August 1, 1996
PubMed
Summary

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Middle-aged men in Stockholm showed improved cardiovascular risk factors over time. Key improvements included lower blood pressure, cholesterol, and glucose, indicating a healthier population in 1991-1992 compared to 1980-1983.

Area of Science:

  • Epidemiology
  • Public Health
  • Cardiovascular Medicine

Background:

  • Comparison of cardiovascular risk factors in urban middle-aged healthy men from two distinct time periods: 1980-1983 and 1991-1992.
  • Utilized control groups from a myocardial infarction study for robust data collection.

Purpose of the Study:

  • To compare cardiovascular risk factor profiles between two cohorts of healthy middle-aged men in Stockholm.
  • To identify changes in risk factors over an approximately ten-year period.

Main Methods:

  • Random selection of subjects from the Stockholm Metropolitan Area population register.
  • Collection of data including weight, height, smoking habits, blood pressure, and blood samples.
  • Analysis of blood and lipoprotein lipid levels, glucose concentrations (fasting and oral glucose tolerance test), and fibrinogen levels.

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Main Results:

  • The 1991-1992 sample exhibited significantly lower systolic blood pressure, total blood cholesterol, fasting blood glucose, and fibrinogen levels compared to the 1980-1983 sample.
  • Decreased total blood cholesterol in the later sample was attributed to reductions in both low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol.
  • A trend towards reduced smoking prevalence was observed in the 1991-1992 cohort, with no significant differences in body mass index, diastolic blood pressure, oral glucose tolerance, or total triglycerides.

Conclusions:

  • Cardiovascular risk factors in urban middle-aged men in Stockholm showed a favorable trend between the early 1980s and early 1990s.
  • Improvements in blood pressure, cholesterol, and glucose levels suggest a potential public health impact on cardiovascular disease risk.
  • While smoking prevalence showed a tendency to decrease, further interventions may be needed to address remaining risk factors.