Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Simulation results with stepwise mutation model and their interpretations

R Chakraborty

    Journal of Molecular Evolution
    |August 5, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Measurement of the Positive Muon Anomalous Magnetic Moment to 127 ppb.

    Physical review letters·2025
    Same author

    A compact frozen-spin trap for the search for the electric dipole moment of the muon.

    The European physical journal. C, Particles and fields·2025
    Same author

    Molecular characterization and virulence of fungal pathogens associated with mass mortalities in hilsa Shad (Tenualosa ilisha).

    Scientific reports·2025
    Same author

    Anomalous spin precession systematic effects in the search for a muon EDM using the frozen-spin technique.

    The European physical journal. C, Particles and fields·2024
    Same author

    Measurement of the Positive Muon Anomalous Magnetic Moment to 0.20 ppm.

    Physical review letters·2023
    Same author

    Coronavirus peplomer interaction.

    Physics of fluids (Woodbury, N.Y. : 1994)·2022

    Monte Carlo simulations show genetic variation models, like the infinite allele model, yield similar heterozygosity distributions. High-frequency alleles are typically older than low-frequency ones.

    Area of Science:

    • Population genetics
    • Molecular evolution

    Background:

    • Understanding genetic variation is crucial for evolutionary studies.
    • Theoretical models like the infinite allele model (IAM) and stepwise mutation model (SMM) are used to study genetic diversity.

    Purpose of the Study:

    • To compare predictions of the IAM and SMM for genetic variation in natural populations.
    • To investigate the relationship between allele frequency and allele age.

    Main Methods:

    • Monte Carlo simulations were employed to model genetic variation.
    • The simulations compared the IAM and SMM under various population parameters.

    Main Results:

    • Heterozygosity distribution showed similarity between IAM and SMM when the product of population size and mutation rate was large.

    Related Experiment Videos

  • Electromorphs with high population frequencies generally represent older alleles compared to those with low frequencies.

    • Conclusions:

    • The IAM and SMM provide comparable predictions for heterozygosity under certain conditions.
    • Allele age correlates with population frequency, offering insights into evolutionary processes at the electrophoretic level.