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Updated: Sep 3, 2026

Implantation of the Syncardia Total Artificial Heart
Published on: July 18, 2014
Current status of heart assist and replacement in Taiwan
Insights
Intraaortic balloon pumps (IABP) are common circulatory assist devices in Taiwan, while extracorporeal membrane oxygenation (ECMO) serves as a good emergency rescue option. Heart transplantation shows promising survival rates, emphasizing the need for organ donation.
Area of Science:
- Cardiovascular Surgery
- Transplantation Medicine
- Critical Care Medicine
Background:
- Intraaortic balloon pumps (IABP) have been clinically used in Taiwan since 1976 for post-cardiotomy cardiogenic shock, becoming a prevalent circulatory assist.
- Extracorporeal membrane oxygenation (ECMO) was introduced in 1987 for intractable heart failure post-transplant, but its use has been limited due to poor outcomes.
- Ventricular assist devices (VADs) are considered for long-term support, with a case highlighting the need for timely implantation before organ failure.
Purpose of the Study:
- To review the clinical applications and outcomes of IABP, ECMO, and heart transplantation in Taiwan.
- To assess the effectiveness and survival rates associated with different circulatory assist devices and heart transplantation.
- To identify factors influencing the success of these advanced cardiac interventions.
Main Methods:
- Retrospective analysis of patient data for IABP, ECMO, and heart transplantation from 1991-1995.
- Evaluation of mortality and survival rates for patients receiving IABP support.
- Assessment of ECMO support outcomes, including weaning and discharge rates.
- Review of heart transplantation data, including operative mortality and actuarial survival rates.
Main Results:
- From 1991-1995, 186 patients received IABP support with a 41.9% overall mortality rate; male patients undergoing coronary artery bypass grafting had a 67% survival rate.
- Between November 1994 and November 1995, 30 patients received ECMO, with 50% weaned and 27% discharged, indicating its utility for short-term or emergency support.
- Between 1991-1995, 102 patients underwent heart transplantation with a 3.9% operative mortality and 1- and 5-year actuarial survival rates of 86% and 77%, respectively.
Conclusions:
- IABP remains a common circulatory assist, while ECMO is valuable for short-term or emergency rescue.
- Heart transplantation in Taiwan has demonstrated favorable survival rates, suggesting the potential for improved outcomes.
- Encouraging organ donation is crucial to enhance the success rates of clinical heart transplantation and improve patient survival.
Abstract:
The first clinical application of intraaortic balloon pumps (IABP) in Taiwan was in 1976 to treat post-cardiotomy cardiogenic shock. It is now the most commonly used circulatory assist. From 1991 to 1995, 186 patients received IABP support with an overall mortality rate 41.9%. The male patients had the best survival rate, 67%, after coronary artery bypass grafting. The first extracorporeal membrane oxygenation (ECMO) was in 1987 to treat intractable heart failure caused by severe acute rejection after heart transplantation. Because of poor outcome, patients only received ECMO sporadically during the past years. From November 1994 to November 1995, 30 patients received ECMO support with 50% of them eventually weaned from ECMO and 27% discharged. For short-term support or emergency rescue, ECMO was a good choice. When long-term support was required, the ventricular assist device (VAD) was a more suitable assist. One patient who received Thermedics VAD developed right heart failure and finally died of sepsis and multiple organ failure. VAD should be implanted before the secondary organ failure. The first successful clinical heart transplantation in Taiwan was performed on July 17, 1987. From 1991 to 1995, 102 patients underwent heart transplantation. The operative mortality was 3.9%, and the 1 and 5 year actuarial survival rates were 86 +/- 3% and 77 +/- 5%, respectively. To improve the success rate of clinical heart transplantation, organ donation should be encouraged.
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