Advances in psychopharmacology--schizophrenia

Every so often in the history of medicine, events occur which in retrospect seem to mark a defining moment. For psychiatry, the decade of the 1950s uses one such 'moment.' On 28 December 1951, J. Sigwald started solo chlorpromazine treatment of a 57-year-old psychotic lady and, thereby, it might be argued, began the modern era of psychopharmacology.