Related Experiment Videos
[Integrins and cadherins: two superfamilies of adhesive receptors]
D Gulino1, E Sulpice, M Alemany
1INSERM 217, Département de Biologie Moléculaire et Structurale, Commissariat à l'Energie Atomique, Grenoble.
Annales D'Endocrinologie
|January 1, 1996
Abstract:
In this paper, two adhesive receptors are presented. The first one, the integrin alpha IIb beta 3 is implied in platelet aggregation following vascular damage. The second one is the VE-cadherin, which is specifically expressed on endothelial cells and participates in the maintenance of endothelium integrity. Their structures and their physiological roles are discussed.