Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

BNCT as a boost for fast neutron therapy?

L Lüdemann1, T Matzen, R Schmidt

  • 1Radiologische Klinik, Universitätskrankenhaus Eppendorf, Hamburg, Germany.

Bulletin Du Cancer. Radiotherapie : Journal De La Societe Francaise Du Cancer : Organe De La Societe Francaise De Radiotherapie Oncologique
|January 1, 1996
PubMed
Summary

This study measured thermal neutron flux using a boron-coated ionization chamber in fast neutron therapy. Results validate a pencil beam algorithm for treatment planning and calculate boron neutron capture therapy (BNCT) boost doses.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Combined radiotherapy and concurrent tumor treating fields (TTFields) for glioblastoma: Dosimetric consequences on non-coplanar IMRT as initial results from a phase I trial.

Radiation oncology (London, England)·2020
Same author

Radiation dose reduction in CT with adaptive statistical iterative reconstruction (ASIR) for patients with bronchial carcinoma and intrapulmonary metastases.

Clinical radiology·2016
Same author

Imaging-Based Liver Function Tests--Past, Present and Future.

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin·2015
Same author

Technical note: Influence of the phantom material on the absorbed-dose energy dependence of the EBT3 radiochromic film for photons in the energy range 3 keV-18 MeV.

Medical physics·2014
Same author

Volumetric assessment of optic nerve sheath and hypophysis in idiopathic intracranial hypertension.

AJNR. American journal of neuroradiology·2013
Same author

Fast 3D Near-infrared breast imaging using indocyanine green for detection and characterization of breast lesions.

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin·2011

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Nuclear Engineering

Background:

  • Accurate measurement of thermal neutron flux is crucial for effective neutron therapy.
  • Boron neutron capture therapy (BNCT) requires precise dosimetry for dose calculation.
  • Fast neutron therapy units necessitate reliable methods for flux characterization.

Purpose of the Study:

  • To measure thermal neutron flux within a fast neutron therapy unit.
  • To compare experimental measurements with a pencil beam algorithm for treatment planning.
  • To calculate the dose contribution of BNCT as a boost therapy.

Main Methods:

  • Utilized a small ionization chamber coated with Boron-10 (10B) to measure thermal neutron flux.
  • Compared measured flux data with calculations from a pencil beam algorithm.

Related Experiment Videos

  • Determined the additional dose for BNCT boost using measured thermal neutron flux.
  • Main Results:

    • Experimental measurements of thermal neutron flux were obtained.
    • The pencil beam algorithm provided a viable first approximation for treatment planning.
    • Calculations for BNCT boost dose were derived from the measured thermal neutron flux.

    Conclusions:

    • The boron-coated ionization chamber is effective for measuring thermal neutron flux in fast neutron therapy.
    • Pencil beam algorithms can serve as a useful tool for initial treatment planning in neutron therapy.
    • The study successfully calculated BNCT boost doses, enhancing treatment precision.