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A tick homologue of the human Ki nuclear autoantigen
1NERC Institute of Virology and Environmental Microbiology, Oxford, UK.
Biochimica Et Biophysica Acta
|November 11, 1996
Abstract:
A clone isolated from a tick salivary gland cDNA library encodes a homologue of the human Ki lupus autoantigen, a protein of unknown function that is related to the subunits of the PA28 proteasome activator. The Ki sequences appear to be well conserved between mammals and invertebrates, with 55% identity between the tick and human primary structures. This is the first report of a Ki homologue in invertebrates.