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Epidemiology of community-acquired Pseudomonas aeruginosa infections in children

I Paraskaki1, E Lebessi, N J Legakis

  • 1Microbiology Department of P. and A. Kyriakou Children's Hospital, Athens, Greece.

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
|October 1, 1996
PubMed

Insights

Community-acquired Pseudomonas aeruginosa infections in children are most common in chronic otitis media. Fortunately, these pediatric Pseudomonas aeruginosa strains show high susceptibility to most antipseudomonadal antibiotics, suggesting effective treatment options.

Area of Science:

  • Pediatric Infectious Diseases
  • Bacteriology
  • Epidemiology

Background:

  • Community-acquired Pseudomonas aeruginosa infections pose a significant challenge in pediatric healthcare.
  • Understanding the epidemiology and antimicrobial susceptibility patterns is crucial for effective treatment.

Purpose of the Study:

  • To evaluate the epidemiology of community-acquired Pseudomonas aeruginosa infections in children.
  • To determine the common types of infections and prevalent serogroups.
  • To assess the antimicrobial susceptibility of isolated strains.

Main Methods:

  • Cultured 6,859 clinical samples from children with suspected infections over one year.
  • Identified Pseudomonas aeruginosa isolates and determined their O serogroups.
  • Tested susceptibility to various antipseudomonadal antibiotics.

Main Results:

  • Pseudomonas aeruginosa was isolated from 218 children, with chronic suppurative otitis media being the most frequent infection (76.3%).
  • Common serogroups included O1, O6, and O11, with nontypable strains predominating in otitis media.
  • Exceptional susceptibility rates were observed for antibiotics like ceftazidime (99.6%), ciprofloxacin (99.1%), tobramycin, imipenem, and amikacin (100%).

Conclusions:

  • Community-acquired Pseudomonas aeruginosa infections in children predominantly affect the ear, particularly chronic otitis media.
  • The high susceptibility of these pediatric isolates to a broad spectrum of antipseudomonadal agents indicates favorable treatment outcomes.

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