Adult solitary cutaneous myofibroma: a case report

The histologic and immunohistochemical features of a case of adult solitary cutaneous myofibroma are reported. The lesion consisted of interlacing bundles of spindle cells arranged around small vessels with hemangiopericytomatous appearance. Neoplastic cells were positive for vimentin and actin. Desmin, cytokeratins and Factor XIIIa were negative. Scattered Langerhans cells positive for S-100 protein and CD1a antigen, usually not reported within this type of neoplasm, were also present.