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Related Experiment Videos

Bromide intoxication due to propantheline bromide

P S Heckerling1, K A Ammar

  • 1Department of Medicine, University of Illinois at Chicago 60612, USA.

American Journal of Nephrology
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

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Bromide poisoning from propantheline bromide caused pneumonia and mental changes in an elderly woman. Spurious hyperchloremia due to bromide interference with chloride tests was key to diagnosis.

Area of Science:

  • Toxicology
  • Clinical Chemistry

Background:

  • Propantheline bromide is an anticholinergic medication.
  • Elderly patients may be more susceptible to medication side effects.

Observation:

  • An elderly woman presented with pneumonia and altered mental status.
  • She had been taking propantheline bromide for two months.

Findings:

  • The patient was diagnosed with bromide poisoning.
  • Bromide interference with serum chloride measurements caused falsely high chloride levels (spurious hyperchloremia).
  • This laboratory anomaly was critical for diagnosing bromide intoxication.

Implications:

  • This case highlights a previously unreported cause of bromide intoxication.

Related Experiment Videos

  • Clinicians should consider bromide poisoning in patients with unexplained symptoms and electrolyte abnormalities.
  • Accurate electrolyte measurement is vital, especially when drug interference is suspected.