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2'3'-CNPase and actin distribution in oligodendrocytes, relative to their mRNAs
1Department of Biochemistry, University of Stirling, Scotland.
Abstract:
By using oligodendrocyte cells, which have a very highly defined cell morphology, it is demonstrated that, in general, proteins are found slightly more distal, relative to the cell body, than their mRNA counterparts, but that there is a general trend for proteins and the messages which encode them to be found in similar regions within the cell. This has been demonstrated by use of in situ hybridization and immunocytochemistry together on single cells.