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Neuro-Behçet disease presenting with internuclear ophthalmoplegia
1Department of Ophthalmology, Faculty of Medicine, Kyoto University, Japan.
Purpose:
To report a case of isolated internuclear ophthalmoplegia in a patient with neuro-Behçet's disease.
Method:
We evaluated the patient's clinical course.
Results:
The patient had isolated internuclear ophthalmoplegia and headache. Subsequent cerebrospinal fluid study revealed marked pleocytosis predominated by lymphocytes (61%) and polymorphonuclear cells (35%), increased protein content, and normal glucose level. A magnetic resonance imaging study with T2-weighted image demonstrated a hyperintense area in the medial longitudinal fasciculus.
Conclusion:
Colchicine treatment of neuro-Behçet's disease caused marked improvement in the symptoms in this case, and the midbrain lesion completely disappeared after treatment.