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Linkage and cytogenetic mapping of a CAG repeat containing human cDNA to 3p24.2-p22
M H Polymeropoulos1, S E Ide, K Becker
1National Center for Human Genome Research, Laboratory of Genetic Disease Research, National Institutes of Health, Bethesda, Maryland 20892, USA.
Cancer Genetics and Cytogenetics
|November 1, 1996
Abstract:
A trinucleotide (CAG)n repeat containing cDNA was isolated from a human cDNA library and sequenced. The locus was mapped by linkage analysis in the CEPH families and by cytogenetic analysis to 3p24.2-p22. We have additionally excluded this gene as a candidate for small cell lung carcinoma by the analysis of cell lines carrying homozygous deletions for the 3p chromosomal region.