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Translocation (6;9;22)(p25;q34;q11.2) identified by FISH in acute leukemia
G J González1, M Notohamiprodjo
1División de Genética, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México.
Cancer Genetics and Cytogenetics
|November 1, 1996
Abstract:
Fluorescence in situ hybridization (FISH) study of bone marrow cells from a patient with clinically and immunologically acute leukemia showed that an apparent t(6;22)(p25; q11.2) identified by routine banding techniques concealed a complex t(6;9;22)(p25;q34; q11.2). This observation further supports the importance of FISH in those cases where a chromosome rearrangement could not be reliably detected by conventional cytogenetic study.