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Psoriasis: pathophysiology and oral manifestations
J F Zhu1, M J Kaminski, D R Pulitzer
1Department of Pediatric Dentistry, University of Texas Health Science Center at San Antonio 78284-7888, USA.
Oral Diseases
|June 1, 1996
Summary
Psoriasis, a chronic inflammatory skin condition, often presents with oral symptoms like tongue and gum lesions. While treatments manage symptoms, a cure for psoriasis remains elusive.
Area of Science:
- Dermatology
- Oral Medicine
- Immunology
Background:
- Psoriasis is a chronic inflammatory skin disease with genetic links, affecting 1-3% of the global population.
- It causes significant disability, social, and economic burdens, yet its mechanisms are not fully understood.
- Research continues to explore the etiology and tissue destruction in psoriasis.
Purpose of the Study:
- To review current literature on psoriasis.
- To specifically highlight the oral manifestations of psoriasis.
- To provide updated information on psoriasis management.
Main Methods:
- Literature review of existing studies on psoriasis.
- Focus on research detailing oral symptoms associated with the condition.
- Synthesis of information regarding treatment strategies.
Main Results:
- Common oral signs include geographic tongue, fissure tongue, and gingival/mucosal lesions.
- Inflammatory temporomandibular joint lesions are reported in fewer than 5% of psoriasis patients.
- Topical and systemic treatments offer symptom relief but not a cure.
Conclusions:
- Psoriasis frequently involves oral manifestations that require attention.
- Current treatments for psoriasis are palliative, not curative.
- Further research is needed to understand and potentially cure psoriasis.