[Two cases of primary mediastinal germ cell tumor]

We have experienced two patients with primary mediastinal germ cell tumor. The 1st case was a 26-year-old male with high AFP levels. The tumor was completely removed with en-bloc resection of the left upper lobe and postoperative combination chemotherapy was effective. He is free of disease for ten years after the surgery. The 2nd case was a 25-year-old male with normal AFP and HCG level. After 2 courses of combined chemotherapy, the residual tumor was resected. Viable tumor cells were not presented in the resected tumor. He is free of disease for 3 months after surgery.