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[Idiopathic segmental anhidrosis]

Y Nakazato1, K Shimazu, N Tamura

  • 1Department of Neurology, Saitama Medical School.

Rinsho Shinkeigaku = Clinical Neurology
|August 1, 1996
PubMed
Summary
This summary is machine-generated.

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Idiopathic segmental anhidrosis, a rare condition affecting localized sweating, was observed in two patients. This suggests a potential link to preganglionic sudomotor nerve lesions, possibly an early form of Ross' syndrome.

Area of Science:

  • Neurology
  • Dermatology
  • Autonomic Nervous System

Background:

  • Idiopathic segmental anhidrosis is a rare condition characterized by localized loss of sweating without a clear cause.
  • Understanding its pathophysiology is crucial for diagnosis and management.

Observation:

  • Two cases are presented: a 47-year-old male with right-sided facial and chest anhidrosis during heating, and a 54-year-old female with left-sided facial and upper chest anhidrosis during exercise.
  • Both patients exhibited normal neurological and autonomic function, except for the localized anhidrosis.

Findings:

  • Pilocarpine-induced sweating was exaggerated in the anhidrotic areas, indicating preganglionic sudomotor nerve lesions.
  • One patient had elevated serum rheumatoid factor; otherwise, laboratory findings were unremarkable.

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  • The condition remained static for over a year in both cases.

    • Implications:

    • Idiopathic segmental anhidrosis may represent an abortive form of Ross' syndrome, which includes tonic pupil, hyporeflexia, and segmental anhidrosis.
    • Further research is needed to elucidate the exact mechanisms and potential associations of this condition.