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Urticarial vasculitis associated with polycythaemia rubra vera
A M Farell1, R A Sabroe, C B Bunker
1Department of Dermatology, Chelsea and Westminster Hospital, London, UK.
Clinical and Experimental Dermatology
|July 1, 1996
Summary
Urticarial vasculitis can be the initial symptom of polycythaemia rubra vera. Treating the polycythaemia with venesection resolved the skin rash, suggesting a direct link.
Area of Science:
- Dermatology
- Hematology
Background:
- Urticarial vasculitis is an inflammatory condition affecting the skin.
- Polycythaemia rubra vera is a myeloproliferative neoplasm characterized by elevated red blood cell mass.
Observation:
- A patient presented with urticarial vasculitis as the primary manifestation.
- The skin eruption was clinically diagnosed as urticarial vasculitis.
Findings:
- The urticarial vasculitis resolved completely following venesection, a procedure to reduce red blood cell count.
- This intervention effectively managed the polycythaemia rubra vera.
Implications:
- This case suggests a potential association between urticarial vasculitis and polycythaemia rubra vera.
- Early recognition of cutaneous symptoms may aid in diagnosing underlying polycythaemia rubra vera.