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Localized scleroderma in breast cancer patients treated with supervoltage external beam radiation: radiation port
D A Davis1, P R Cohen, M D McNeese
1Department of Dermatology, University of Texas, Medical Branch, Galveston 77555, USA.
Background:
An association between systemic scleroderma, radiation, and breast cancer has been recognized. However, localized scleroderma in the radiation port of breast cancer patients has been rarely described.
Objective:
Our purpose was to describe the concurrence of localized scleroderma, supervoltage radiation, and breast carcinoma.
Methods:
Patients were prospectively evaluated in a tertiary care cancer center, and the literature was reviewed.
Results:
We describe six patients with breast cancer in whom localized scleroderma developed within their radiation port.
Conclusion:
Radiation port localized scleroderma can be a sequela of supervoltage radiation therapy in patients with breast cancer. Recognition is important because localized scleroderma can clinically mimic recurrent breast carcinoma.