Cardiac surgery for Kartagener syndrome
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Updated: Nov 3, 2026

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
T Tkebuchava1, L K von Segesser, U Niederhäuser
1Clinic for Cardiovascular Surgery, University Hospital, Zurich, Switzerland.
Insights
Children with Kartagener syndrome and heart defects can undergo successful cardiac surgery. Long-term outcomes show good physical activity and no need for heart medication.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Surgery
- Genetics and Rare Diseases
Background:
- Kartagener syndrome is a rare genetic disorder characterized by situs inversus, chronic sinusitis, and bronchiectasis.
- Patients with Kartagener syndrome may present with associated congenital cardiac anomalies, complicating management.
- Surgical intervention for congenital heart disease in these patients requires careful consideration due to potential pulmonary complications.
Abstract:
Two patients (one girl, one boy) with Kartagener syndrome (situs inversus, bronchiectasis, sinusitis), despite pulmonary problems and associated congenital cardiac anomalies, were operated on at the ages of 4 years and 7 years, respectively. They had had previous palliative treatment at the age of 3 months and 1.3 years, respectively. Both postoperative periods after total correction were without significant complications. Long-term follow-up was available for 9 and 19 years, respectively, with no manifestations of heart insufficiency. Both patients are physically active, and neither requires cardiac medication. Patients with Kartagener syndrome and associated congenital cardiac anomalies can successfully undergo multiple cardiac operations with good long-term outcome.
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