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Updated: Aug 18, 2026

Generation and Multi-phenotypic High-content Screening of Coxiella burnetii Transposon Mutants
Published on: May 13, 2015
Genetics of Coxiella burnetii
1Department of Microbiology and Immunology, School of Medicine, West Virginia University, Morgantown 26506-9177, USA. thompson@wvumbiml.hsc.wvu.edu
Abstract:
Those organisms considered to be obligate intracellular bacteria are interesting objects for genetic studies. Little is known about their mechanisms for natural genetic exchange. Many genes from the bacterium Coxiella burnetii, an obligate intraphagolysosomal pathogen, have therefore been cloned and characterized using the heterologous host Escherichia coli. Recently, use of electroporation methodology followed by long-term selection periods have provided initial data on genetic transformation in C. burnetii.
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