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Updated: Aug 21, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
[Malignant melanoma of the nasal cavity and paranasal sinuses]
J P Rodrigo Tapia1, I Alvarez Alvarez, J A Fernández Martínez
1Servicio de ORL, Hospital Central de Asturias, Universidad de Oviedo.
Abstract:
Malignant melanomas represent about 3% of all nasosinusal neoplasms. They usually are located in the nasal septum and their maximum incidence is in the sixth and seventh decades. In the early stages they are asymptomatic, which delays diagnosis and reduces the possibilities of cure to 15-30%. Eight cases of nasosinusal melanoma are reported and their characteristics are reviewed with special attention to prognostic factors.
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