[Invasion of the optic nerve in undifferentiated retinoblastoma]

The case of a 2- and a half-year-old child is presented. The diagnosis was left-eye retinoblastoma and the left-eye enucleation was done. The anatomic-pathological exam emphasizes a microscopic structure of undifferentiated retinoblastoma, with the invasion of the optic nerve. After about 11 months, the child came again, presenting a tumoral mass which occupies almost entirely the orbital cavity, and also an altered general status.