Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Na/Ca exchange]

A Herchuelz1

  • 1Laboratoire de Pharmacodynamie et de Thérapeutique, faculté de Médecine, Université libre de Bruxelles.

Bulletin Et Memoires De L'Academie Royale De Medecine De Belgique
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

Sodium-calcium exchange (Na/Ca) is vital for regulating cell calcium. Recent molecular advances highlight its critical role in cardiac cells and potential in understanding cardiac ischemia.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preconditioning in hypoxic-ischemic neonate mice triggers Na<sup>+</sup>-Ca<sup>2+</sup> exchanger-dependent neurogenesis.

Cell death discovery·2022
Same author

β-Cell preservation and regeneration in diabetes by modulation of β-cell Ca²⁺ homeostasis.

Diabetes, obesity & metabolism·2012
Same author

The suppressor of cytokine signalling 2 (SOCS2) is a key repressor of insulin secretion.

Diabetologia·2010
Same author

Pancreatic islet function in omega-3 fatty acid-depleted rats: alteration of calcium fluxes and calcium-dependent insulin release.

American journal of physiology. Endocrinology and metabolism·2006
Same author

Na/Ca exchange and Ca2+ homeostasis in the pancreatic beta-cell.

Diabetes & metabolism·2003
Same author

The SleepStrip: an apnoea screener for the early detection of sleep apnoea syndrome.

The European respiratory journal·2002
Same journal

[Belgium Royal Academy of Medicine membership list].

Bulletin et memoires de l'Academie royale de medecine de Belgique·2015
Same journal

Massively parallel sequencing: a new tool in virus discovery and vaccine safety.

Bulletin et memoires de l'Academie royale de medecine de Belgique·2012
Same journal

New viral pathogens from wildlife.

Bulletin et memoires de l'Academie royale de medecine de Belgique·2012
Same journal

Liver transplantation or Starzl's legacy. A look backward, a look forward.

Bulletin et memoires de l'Academie royale de medecine de Belgique·2012
Same journal

[The creation of a vascularized tracheal transplantation].

Bulletin et memoires de l'Academie royale de medecine de Belgique·2012
Same journal

[Molecular dialogue between African trypanosomes and humans].

Bulletin et memoires de l'Academie royale de medecine de Belgique·2012
See all related articles

Area of Science:

  • Physiology
  • Molecular Biology
  • Cell Biology

Background:

  • Sodium-calcium exchange (Na/Ca) is a key regulator of intracellular calcium levels in most cells.
  • It functions alongside the plasma membrane Ca2+ ATPase to actively remove calcium from cells.
  • Recent molecular biology advances have renewed interest in this system.

Purpose of the Study:

  • To explore the molecular mechanisms of the Na/Ca exchanger.
  • To elucidate the role of Na/Ca exchange in cardiac cell calcium extrusion.
  • To understand the physiological and pathophysiological implications of Na/Ca exchange, particularly in cardiac ischemia.

Main Methods:

  • Molecular biology techniques to study the Na/Ca exchanger.
  • Cellular assays to measure calcium extrusion.

Related Experiment Videos

  • Physiological studies focusing on cardiac function.

    • Main Results:

    • Advances in understanding the molecular biology of the Na/Ca exchanger.
    • Identification of the exchanger's significant role in cardiac calcium extrusion.
    • Potential for improved understanding of Na/Ca's role in health and disease.

    Conclusions:

    • Na/Ca exchange is a critical system for cellular calcium homeostasis.
    • The exchanger plays a major role in cardiac calcium regulation.
    • Further research may lead to better management of conditions like cardiac ischemia.