Related Experiment Video
Updated: Oct 13, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Clinical monitoring using regression-based trend templates
I J Haimowitz1, P P Le, I S Kohane
1General Electric Corporate Research and Development, Schenectady, NY 12309, USA.
Abstract:
Our computer program TrenDx detects clinically significant trends in time-ordered patient data by matching data to patterns called trend templates, denoting multivariate temporal and value variation in normality and in disease. Previously a purely constraint-based TrenDx diagnosed pediatric growth trends and reached the same diagnoses as a panel of experts, at a time no later than the experts, in most of 30 cases. Improvement required resolving outstanding representational issues. In this paper we describe regression-based trend templates, updated TrenDx algorithms, and their application to monitoring intensive care unit and pediatric growth data. We focus on new results in diagnosing pediatric growth trends, and discuss potential application domains for TrenDx.
Related Concept Videos
Regression Toward the Mean
Regression Analysis
In regression analysis, a regression equation is determined based on the line of best fit– a line that best fits the data points plotted in a graph. This line is also called the regression line. The algebraic equation for the regression line is called the regression equation. It is represented as:
Residuals and Least-Squares Property
If the observed data point lies above the line, the residual is positive, and the line underestimates the actual data value for y. If the observed data point lies below the line, the residual is negative, and the line overestimates the actual data value for y.
The process of fitting the best-fit...
Run Charts
Interpreting Run Charts
Microsoft Excel: Regression Analysis
To perform regression...
