[Changes in calcium metabolism in osteoarthrosis in miners]

The studies covered serum levels of total and ionized calcium (Ca), parathyroid hormone (PTH), calcitriol (Ctr) and calcitonin (Ct) in miners assigned to various occupational groups and suffering from deforming osteoarthrosis. Ratio of calcium clearance to glomerular filtration rate was assessed. Ionized Ca appeared to decrease along with increase of PTH and Ctr. Changes in Ca homeostasis were proved to depend on occupation, geologic conditions in the mines (depth, ambient temperature of the workplace), presence of chondrocalcinosis.