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Eye infections after refractive keratotomy

S Jain1, D T Azar

  • 1Wilmer Institute, Johns Hopkins University, Baltimore, Md., USA.

Journal of Refractive Surgery (Thorofare, N.J. : 1995)
|January 1, 1996
PubMed
Summary
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Ocular infections following refractive keratotomy can threaten vision. Key risk factors include reoperations, contact lens wear, and intraoperative perforations, with infections often occurring within two weeks.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Surgical Complications

Background:

  • Ocular infections are serious complications after refractive keratotomy.
  • These infections can potentially threaten vision.
  • An integrative review addresses key issues regarding these complications.

Purpose of the Study:

  • To review published literature on infections after refractive keratotomy.
  • To identify important issues and risk factors associated with these complications.
  • To analyze the characteristics and outcomes of ocular infections post-refractive surgery.

Main Methods:

  • Systematic identification and review of articles from MEDLINE, published manuscripts, and abstracts.
  • Inclusion of previously unpublished cases of infection after refractive keratotomy.

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  • Exclusion of relaxing incisions for postkeratoplasty astigmatism and abstraction of pertinent data.

    • Main Results:

    • 43 cases (47 episodes) of infection (42 keratitis, 5 endophthalmitis) reported between 1975-1994.
    • Infections occurred within 2 weeks in 47% of eyes, predominantly in the inferior cornea.
    • Bacterial infections (66%) were most common; reoperations, contact lens wear, and intraoperative perforations were potential associations.

    Conclusions:

    • Infections after refractive keratotomy can compromise visual function.
    • Approximately 50% of infections manifest within the first two weeks post-surgery.
    • Reoperations, postoperative contact lens wear, and intraoperative perforations are significant risk factors.