[Temperature distribution pattern in liver tissue in freezing procedures with new cryoprobes]
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Updated: Jul 29, 2026

Technique of Subnormothermic Ex Vivo Liver Perfusion for the Storage, Assessment, and Repair of Marginal Liver Grafts
Published on: August 13, 2014
W K Berger1, G Schüder, G Feifel
1Abteilung Allgemeine Chirurgie. Abdominal-und Gefässchirurgie, Chirurgische Universitätsklinik Homburg/Saar.
Abstract:
The performance of new cryoprobes was studied by measuring the spatial and temporal patterns of the temperature distribution in liver tissue around one to three active cryoprobes. After 15 min of maximal freezing a tissue region 22 mm in diameter was frozen to temperatures below - 50 degrees C by one active cryoprobe. With three cryoprobes, using the synergistic cooling effect, a tissue region 45 mm in diameter was cooled to temperatures below - 50 degrees C. Optimal placement of the cryoprobes was found to be of critical importance.

