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[Effect of glutaryl-lecithins on human erythrocytes (author's transl)]
Abstract:
Effect of glutaryl-lecithins on red blood cells is studied and compared to effect to egg lysolecithins. 1. Glutaryl-lecithins exhibit a hemolytic activity which appears in the first minutes. The rate of hemolysis increases proportionally with glutaryllecithin concentration up to concentrations of 1 X 10(-7) mole. 2. Glutaryl-lecithins methylation causes a decrease of lytic activity; this might indicate that the carboxylic group plays a role in the process of hemolysis. 3. Glutaryl-lecithins can produce echinocytes, in a similar fashion to lysolecithins. These findings suggest that glutaryl-lecithin hemolytic activity plays an important role in the process of post irradiation hemolysis.