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Morvan's fibrillary chorea: remission after plasmapheresis
A Madrid1, A Gil-Peralta, E Gil-Néciga
1Servicio de Neurología, Hospital Universitario Virgen del Rocío, Sevilla, Spain.
Journal of Neurology
|April 1, 1996
Summary
Plasmapheresis effectively treated Morvan's fibrillary chorea in two patients. This novel therapeutic approach significantly improved neurological symptoms, offering new hope for managing this rare condition.
Area of Science:
- Neurology
- Immunology
Background:
- Morvan's fibrillary chorea is a rare autoimmune neurological disorder.
- Current treatment options for Morvan's fibrillary chorea are limited.
Observation:
- Two patients diagnosed with Morvan's fibrillary chorea were assessed.
- One patient also presented with sigmoid carcinoma, cerebrospinal fluid oligoclonal bands, and altered muscle lipid-oxidative patterns.
Findings:
- Plasmapheresis, a blood purification technique, was administered to both patients.
- A marked improvement in the clinical symptoms of Morvan's fibrillary chorea was observed post-treatment.
Implications:
- This study suggests plasmapheresis as a potentially effective therapeutic strategy for Morvan's fibrillary chorea.
- Further research is warranted to confirm these findings and explore the underlying mechanisms.