Related Experiment Video
Updated: Aug 18, 2026

Mouse Model of Alloimmune-induced Vascular Rejection and Transplant Arteriosclerosis
Published on: May 17, 2015
[Autoarterial grafts for myocardial revascularization and their morphological assesment in coronary heart disease]
Insights
Internal thoracic arteries and epigastric inferior arteries are less prone to atherosclerosis, making them suitable for myocardial revascularization. Arteriography is recommended for optimal graft selection.
Area of Science:
- Vascular Surgery
- Cardiology
- Anatomy
Background:
- Myocardial revascularization relies on suitable arterial grafts.
- Understanding graft morphology and disease susceptibility is crucial.
Purpose of the Study:
- To compare the morphology and atherosclerotic profiles of three arterial grafts: thoracic internal artery, right gastro-epiploic artery, and inferior epigastric artery.
- To evaluate their suitability for myocardial revascularization.
Main Methods:
- Comparative analysis of arterial grafts in cadavers.
- Morphological assessment and evaluation of atherosclerotic process.
- Testing of 55 thoracic internal arteries, 52 right gastro-epiploic arteries, and 34 inferior epigastric arteries.
Main Results:
- Thoracic internal artery is elastic-type; gastro-epiploic and inferior epigastric arteries are muscle-type.
- Thoracic internal and inferior epigastric arteries showed rare atherosclerosis under 60.
- Gastro-epiploic artery had more non-stenotic lesions; older individuals (>60) showed more stenotic lesions in thoracic internal and inferior epigastric arteries.
Conclusions:
- Thoracic internal and inferior epigastric arteries are less affected by atherosclerosis, especially in younger individuals.
- Gastro-epiploic artery shows higher prevalence of atherosclerotic lesions.
- Arteriography is essential for selecting the most appropriate arterial graft for myocardial revascularization.
Abstract:
A comparative analysis of arterial grafts used for myocardial revascularization has been done. The morphology of arteries, rate and degree of atherosclerotic process were evaluated. 55 thoracic internal arteries, 52 right gastro-epipiolcal arteries, 34 epigastrical inferior arteries have been tested in cadavers of people with signs of coronary heart disease. Arteria thoracica interna appeared to be a vessel with prevalence of elastic elements, while arteria gastro-epiplocia and arteria epigastrica inferior are predominantly muscle-type. Arteria thoracica interna and arteria epigastrica inferior appeared to be rarely affected with atherosclerosis in people under 60 years of age. Atherosclerotic lesions have been found more often in arteria gastro-epiploica without stenotic lesions. In people over 60 years of age the stenotic lesions in arteria thoracica interna and arteria epigastrica are found much more often than in arteria gastro-epiploica. Arteriography should be done in selecting the proper graft for myocardial revascularization.
More Related Videos
09:12Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
05:25Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023