Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Primary leiomyosarcoma of the bone]

B M Delsmann1, F W Hagena, A Nerlich

  • 1Orthopädische Klinik und Poliklinik, Ludwig-Maximilians-Universität München-Klinikum Grosshadern.

Zeitschrift Fur Orthopadie Und Ihre Grenzgebiete
|September 1, 1996
PubMed
Summary

Primary bone leiomyosarcoma is a rare and aggressive cancer with a 50% mortality rate. Early diagnosis through histopathology and immunohistochemistry is crucial for effective treatment, with surgery as the primary option.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Surgical Outcome and Oncological Survival of Osteofibrous Dysplasia-Like and Classic Adamantinomas: An International Multicenter Study of 318 Cases.

The Journal of bone and joint surgery. American volume·2020
Same author

Hydroxy-chloroquine to treat COVID-19 - infected patients: Some lessons from medical anthropology and history of medicine.

Ethics, medicine, and public health·2020
Same author

[Diagnosis and therapy of benign intraarticular tumors].

Der Orthopade·2017
Same author

Dynamic Virus-Bacterium Interactions in a Porcine Precision-Cut Lung Slice Coinfection Model: Swine Influenza Virus Paves the Way for Streptococcus suis Infection in a Two-Step Process.

Infection and immunity·2015
Same author

[Free Gracilis Flap for Anatomic Reconstruction after Limb-sparing Sarcoma Resection].

Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V...·2015
Same author

Unusual spinal tuberculosis in an Avar Age skeleton (Csongrád-Felgyő, Ürmös-tanya, Hungary): A morphological and biomolecular study.

Tuberculosis (Edinburgh, Scotland)·2015

Area of Science:

  • Oncology
  • Pathology
  • Surgical Oncology

Background:

  • Primary leiomyosarcoma of the bone is an exceptionally rare malignant tumor.
  • This condition carries a significant mortality rate of 50% and a mean survival time of 3.4 years post-diagnosis.

Observation:

  • The study presents two cases: a 52-year-old female with stage IIIb right distal femur tumor and a 50-year-old patient with stage Ia left distal tibia tumor.
  • Both patients were diagnosed with primary bone leiomyosarcoma.

Findings:

  • Accurate diagnosis requires excluding secondary leiomyosarcoma and involves detailed histopathological and immunohistochemical examination.
  • Surgical intervention is the preferred treatment modality for primary bone leiomyosarcoma.

Implications:

Related Experiment Videos

  • The findings underscore the importance of accurate diagnostic methods for this rare bone sarcoma.
  • Multimodal treatment approaches, potentially including neoadjuvant or adjuvant radio- or chemotherapy, may improve patient outcomes.