[Liver function and the lipid metabolic status of patients before and after a surgical intervention on the...

Local hepatic bloodflow (LHB) and metabolic processes were examined in patients with abdominal diseases during intensive transfusion and infusion therapy attended by incomplete parenteral feeding. A reduction of LHB and disorders of lipid metabolism were observed before surgery. After surgery LHB was still reduced on days 1-3. Cholestatic and cytolytic syndromes developed after the intervention, and a reduction of the protein-synthesizing function of hepatocytes and disorders of the lipid status were observed. By days 7-10 the protein-synthesizing function recovered, as did the enzymatic activity, but no complete recovery of LHB and lipid spectrum were observed.