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Updated: Aug 18, 2026

A Reference Broth Microdilution Method for Dalbavancin In Vitro Susceptibility Testing of Bacteria that Grow Aerobically
Published on: September 9, 2015
[Pharmacokinetics of vancomycin in neonates of postconceptional age less than or equal to 32 weeks]
G Ginovart Galiana1, M A Mangues Bafalluy, X Demestre Guasch
1Unidad de Neonatología, Hospital de la Santa Creu i Sant Pau, Barcelona.
Abstract:
The objective of the present study was to analyze the pharmacokinetic behavior of vancomycin in neonates of postconceptional age < or = 32 weeks (n = 44). The elimination of the antibiotic was influenced by the concomitant treatment with indomethacin and mechanical ventilation. Close monitoring of renal function of the neonate and vancomycin dosage individualization are mandatory when the above factors are present. Vancomycin dosage guidelines have been determined according to serum creatinine of these premature patients.
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