[Chemotherapy of malignant tumors]

Potentialities and principles of cancer chemotherapy, the approaches to the search of new cytostatics are shown. Modern chemotherapy is, as a rule, a combination chemotherapy with simultaneous use of 3-4 cytostatics with different mechanism of action and various toxicity. Chemotherapy is a method of choice not only in hemoblastosis, but in such solid tumours as uterine chorionepithelioma, testicular seminoma, Wilms tumour, lung small cell carcinoma, etc. In case of responsive tumours chemotherapy may result in complete recovery of 8 to 80% of patients.