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Related Experiment Videos

[Propofol (Diprivan) in emergency anesthesia]

B Badeva, I Vankov, D Bochev

    Khirurgiia
    |January 1, 1996
    PubMed
    Summary

    Total intravenous anesthesia (TIVA) using propofol, alfentanil, and atracurium offers controlled anesthesia for high-risk patients. This combination provides effective hypnosis, analgesia, and muscle relaxation with reduced drug dosages.

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    Area of Science:

    • Anesthesiology
    • Pharmacology

    Background:

    • Total intravenous anesthesia (TIVA) is a method of anesthesia delivery.
    • Propofol, alfentanil, and atracurium are commonly used anesthetic agents.

    Purpose of the Study:

    • To assess the efficacy and control of TIVA using propofol, alfentanil, and atracurium.
    • To evaluate pharmacokinetic and pharmacodynamic control of TIVA in high-risk surgical patients.

    Main Methods:

    • A cohort of 15 patients with ASA III-IV classification received TIVA.
    • Drug dosages and infusion techniques were described.
    • Respiratory and cardiocirculatory parameters were monitored.

    Main Results:

    • Reduced dosages of propofol (4-5 mg/kg/h) and alfentanil (1-1.5 mg/h) were effective in maintaining anesthesia.

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  • Prophylaxis against operative stress was rated as very good.
  • TIVA with this drug combination demonstrated excellent controllability.

    • Conclusions:

    • TIVA with propofol, alfentanil, and atracurium provides a controllable anesthetic technique.
    • This combination is suitable for patients with increased anesthesiological risk.
    • The study supports the use of TIVA for improved anesthetic management.