[Propofol in combination with etomidate for anesthesia induction]

Assessment of the joint effect of propofol (Diprivan) and etomidat on hemodynamics and side effects is carried out in a series of 60 patients with ASA I--IV, divided up into two groups of thirty cases each. A single dose of 2.2 mg/kg(-1) propofol brings about safe anesthesia induction. In the event of anesthesia induction being preceded by fentanyl and lormetasepame injections, the propofol dose is reduced to 1.8 mg/kg(-1). The hemodynamics, against the background of an insignificant effect on the patient's post-sedation AP, shows an increase by 10-12 mm Hg, and throughout the anesthesia it remains higher, as compared to that in patients given etomidat. Analysis of the side effects shows isolated cases of flush, fasciculations and the like, prevailing in etomidat cases. Complaints of pain at venipuncture site after propofol are very few. In conclusion, propofol and etomidat account for favourable conditions of anesthesia induction, as well as for short-lasting anesthesia.