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[Biochemical modulation applied to experimental cancer chemotherapy]

Y Nakamura1

  • 1Department of Otolaryngology, Teikyo University, School of Medicine, Tokyo.

Summary

Leucovorin (LV) enhances the antitumor effect of 5-fluorouracil (5-FU) in human tumor xenografts and clonogenic assays. Administering LV one hour before 5-FU and using continuous contact methods improved efficacy.

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