Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Rosette-forming non-Hodgkin's lymphomas

C H Koo1, S S Shin, F Bracho

  • 1Department of Pathology, Kaiser Foundation Hospital, Los Angeles, California, USA.

Histopathology
|December 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimal water supply reservoir operation by leveraging the meta-heuristic Harris Hawks algorithms and opposite based learning technique.

Scientific reports·2023
Same author

Accelerated rehabilitation following thumb ulnar collateral ligament repair with suture tape augmentation: A case series of professional basketball players.

Journal of hand therapy : official journal of the American Society of Hand Therapists·2022
Same author

Can we do it faster? accelerated rehabilitation following thumb ulnar collateral ligament repair with suture tape augmentation.

Journal of hand therapy : official journal of the American Society of Hand Therapists·2021
Same author

Impact of mental disorders on active TB treatment outcomes: a systematic review and meta-analysis.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2020
Same author

Integrating tuberculosis and mental health services: global receptivity of national tuberculosis program directors.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2019
Same author

Comparison between the effects of deep and moderate neuromuscular blockade during transurethral resection of bladder tumor on endoscopic surgical condition and recovery profile: a prospective, randomized, and controlled trial.

World journal of urology·2018
Same journal

Flat epithelial atypia of the breast: a pragmatic, context-integrated diagnostic framework within a biological continuum.

Histopathology·2026
Same journal

Myxoid neoplasms with MAP3K kinase fusion: a study of 39 cases.

Histopathology·2026
Same journal

TROP2 immunoreactivity in pulmonary large cell neuroendocrine carcinoma.

Histopathology·2026
Same journal

Malignant adenomyoepithelioma of the breast: seven cases illustrating morphological diversity and diagnostic challenges.

Histopathology·2026
Same journal

A CRX-positive RB1-deficient bone tumour with a retinoblastoma-like DNA methylation profile.

Histopathology·2026
Same journal

Perivascular epithelioid cell tumours of the genitourinary tract: clinicopathological features and molecular landscape.

Histopathology·2026
See all related articles

Homer Wright rosettes, previously linked to neuroblastomas, can also appear in malignant lymphomas. This finding expands the differential diagnosis for rosette-forming small round cell tumors.

Area of Science:

  • Oncology
  • Pathology

Background:

  • Homer Wright rosettes are characteristic of neuroblastomas and aid in diagnosing small round cell tumors.
  • Their presence in lymph nodes or bone marrow traditionally ruled out malignant lymphoma.

Observation:

  • This report details three cases of malignant lymphoma (two small lymphocytic, one diffuse large cell) exhibiting prominent rosette formation.
  • The rosettes were composed of neoplastic lymphoid cells, sometimes with reactive macrophages, and featured a central fibrillary core.

Findings:

  • Two lymphomas were B-cell lineage, and one was T-cell lineage, marking the first reported instance of T-cell lymphoma with rosettes.
  • Ultrastructural analysis revealed interdigitating cytoplasmic projections within the rosettes.

Implications:

Related Experiment Videos

  • Malignant lymphomas, particularly non-Hodgkin's lymphoma, should be considered in the differential diagnosis of neoplasms with rosette formation.
  • This challenges previous diagnostic assumptions and broadens the understanding of lymphoma morphology.