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Related Experiment Videos

Thick blood syndrome

R L Wesenberg, C M Rumack, L O Lubchenco

    Radiology
    |October 1, 1977
    PubMed
    Summary
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    Hyperviscosity syndrome in neonates presents with specific radiological findings like increased pulmonary vascularity. Exchange transfusion can improve these findings, suggesting a treatable cause of neonatal central nervous system damage.

    Area of Science:

    • Neonatal radiology
    • Pediatric hematology
    • Neonatal neurology

    Background:

    • Hyperviscosity syndrome is a condition characterized by increased blood viscosity.
    • Its radiological manifestations in neonates require further elucidation.
    • Understanding its impact on neonatal health is crucial.

    Observation:

    • Prospective study of twenty neonatal hyperviscosity cases.
    • Serial chest radiographs were utilized to identify radiological findings.
    • Assessment of the effect of exchange transfusion on these findings.

    Findings:

    • Common radiological findings include increased pulmonary vascularity, hyperaeration, and bilateral alveolar infiltrates.
    • Partial plasma exchange transfusion led to improvement in observed radiological signs.

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  • Hyperviscosity syndrome appears to be more prevalent than previously thought.

    • Implications:

    • Hyperviscosity syndrome is a significant, potentially treatable cause of neonatal central nervous system damage.
    • Early identification and intervention with exchange transfusion may mitigate neurological sequelae.
    • Further research into the long-term neurological outcomes is warranted.