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Persistent severe hypertension in an infant with posterior urethral valves
D G Muchant1, J M Gloor, L L Norling
1Division Pediatric Nephrology, University of West Virginia, Morgantown, USA.
Insights
Severe hypertension in infants is rare and often secondary. This case highlights segmental renal artery stenosis as a cause of severe hypertension in an infant with reflux nephropathy, resistant to medication.
Area of Science:
- Pediatric Nephrology
- Cardiovascular Medicine
- Medical Imaging
Background:
- Severe hypertension is uncommon in pediatric patients and typically stems from a specific secondary cause.
- Reflux nephropathy is a recognized contributor to secondary hypertension in children.
- Infants presenting with severe hypertension warrant thorough investigation for underlying causes.
Abstract:
Severe hypertension, an infrequent problem in pediatrics, usually has a single secondary cause. We report an infant with severe hypertension and left reflux nephropathy, a known cause of secondary hypertension. The severity of hypertension and poor response to pharmacological therapy prompted further investigation, including a renal arteriogram that showed a right segmental renal artery stenosis.