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Related Experiment Videos

Sonographic patterns in extranodal abdominal lymphomas

C Görg1, R Weide, W B Schwerk

  • 1Department of Internal Medicine, Philipps-University, Marburg, Germany.

European Radiology
|January 1, 1996
PubMed
Summary

Ultrasonography effectively diagnosed extranodular abdominal lymphoma infiltrates in patients with non-Hodgkin's lymphoma (NHL) and Hodgkin's disease (HD). Specific sonographic patterns correlated with lymphoma subtypes, aiding clinical management.

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Area of Science:

  • Radiology
  • Oncology
  • Medical Imaging

Background:

  • Extranodular abdominal involvement is common in non-Hodgkin's lymphoma (NHL) and Hodgkin's disease (HD).
  • Accurate diagnosis and characterization of these infiltrates are crucial for effective patient management.

Purpose of the Study:

  • To evaluate the diagnostic utility of ultrasonography in identifying extranodular abdominal lymphoma infiltrates.
  • To describe sonographic features of lymphoma in various extranodal sites.
  • To investigate correlations between lymphoma subtypes and sonographic characteristics.

Main Methods:

  • Prospective ultrasonography study of 680 patients with NHL or HD between 1980 and 1993.
  • Diagnosis of 254 extranodular abdominal lymphoma infiltrates in 210 patients.

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  • Histological and clinical confirmation of infiltrates.
  • Analysis of sonographic features and patterns.
  • Main Results:

    • Ultrasonography diagnosed extranodular abdominal lymphoma infiltrates in 210 of 680 patients.
    • Most frequent sites included spleen (n=101), gastrointestinal tract (n=70), liver (n=47), and kidneys (n=17).
    • Distinct sonographic patterns were observed: high-grade NHLs showed large-nodular lesions, while low-grade NHLs and HD exhibited small-nodular or diffuse patterns, particularly in the liver and spleen.

    Conclusions:

    • Ultrasonography is a valuable tool for detecting and characterizing extranodular abdominal lymphoma infiltrates.
    • Sonographic features can help differentiate between lymphoma subtypes, aiding in clinical decision-making.
    • The findings support the role of ultrasonography in the comprehensive management of lymphoma patients.