Related Experiment Videos
Nodular regenerative hyperplasia of the liver in a patient with systemic sclerosis
J Kaburaki1, S Kuramochi, T Fujii
1Department of Internal Medicine, Keio University School of Medicine, Japan.
Abstract:
We report on a 33-year-old female patient with systemic sclerosis and nodular regenerative hyperplasia of the liver (NRHL). A needle biopsy of the patient's liver did not reveal the histology of NRHL or liver cirrhosis at her first visit to our hospital, when portal hypertension was demonstrated by percutaneous transhepatic portography. After 11 years, the patient died of hepatic and renal failure. At the time of autopsy, multiple nodules were found in the liver, and a microscopic examination showed a histology compatible with NRHL. It is suggested that the immunological disturbance was related to the patient's portal hypertension and NRHL.