[Correlation of changes in the electrical activity and indices of tissue respiration of brain structures in rabbits...

The electrical activity and tissue respiration of the cortex and subcortex (posterior hypothalamic nucleus, Deiters' vestibular nucleus) have been studied in the rabbits during 3-month exposure to vibration (60H2, for 3h daily). On days 15-30 of exposure to vibration the electrocorticogram demonstrated the prevalence of alfa-waves whereas in the subcortex the teta-waves were dominated. On long-term vibration exposure (2-3 months), the synchronized slow waves were recorded on the EEG. Comparison of a changed electrical activity of the various structures of the brain with the level of oxidizing metabolism enabled us to reveal their definite interrelationship. In the early stage of vibration exposure there has been observed an increased absorption of oxygen by the brain structures and the elevated activity of succinate dehydrogenase. The prolonged vibration resulted in a decreased level of tissue respiration and activity of respiratory enzyme. Under vibration exposure there has been revealed a statistically significant direct relationship between the content of absorbed oxygen, activity of succinate dehydrogenase and the shifts in the electrical activity of cerebral structures.