Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Hyperuricosuria and urolithiasis]

T Koide1

  • 1Department of Urology, Osaka Kosei-Nenkin Hospital.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|December 1, 1996
PubMed
Summary
This summary is machine-generated.

Hyperuricosuria, a common cause of urinary stones, often leads to calcium oxalate or uric acid stones. Treating high uric acid levels is crucial for preventing recurrent urinary stone formation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Systematic analysis of emotionality in consomic mouse strains established from C57BL/6J and wild-derived MSM/Ms.

Genes, brain, and behavior·2008
Same author

Microscopic formula for transport coefficients of causal hydrodynamics.

Physical review. E, Statistical, nonlinear, and soft matter physics·2007
Same author

Chemically modified thrombin and anhydrothrombin that differentiate macromolecular substrates of thrombin.

Journal of thrombosis and haemostasis : JTH·2005
Same author

Microscopic derivation of causal diffusion equation using the projection operator method.

Physical review. E, Statistical, nonlinear, and soft matter physics·2005
Same author

Enhanced blood coagulation and fibrinolysis in mice lacking histidine-rich glycoprotein (HRG).

Journal of thrombosis and haemostasis : JTH·2005
Same author

[Surgical management of papillary muscle rupture following acute myocardial infarction].

Kyobu geka. The Japanese journal of thoracic surgery·2005
Same journal

[Development of novel therapeutics for multiple myeloma and improvement of drug lag].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Clinical pharmacy services to patients of immunomodulatory drugs].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Therapeutic drug monitoring of the new anti-myeloma drugs in the treatment of multiple myeloma].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Prognostic value of minimal residual disease assessment using next-generation sequencing in multiple myeloma].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[The evaluation of minimal residual disease in multiple myeloma by an allele-specific oligonucleotide real-time PCR].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Evaluation of minimal residual disease in myeloma by multiparametric flow cytometry].

Nihon rinsho. Japanese journal of clinical medicine·2019
See all related articles

Area of Science:

  • Nephrology
  • Urology
  • Biochemistry

Context:

  • Hyperuricosuria is a significant factor in urolithiasis.
  • Approximately 23% of urolithiasis cases are linked to hyperuricosuria.
  • This condition contributes to both calcium oxalate and uric acid stones.

Purpose:

  • To explore the role of uric acid in calcium oxalate stone formation.
  • To investigate the mechanisms by which uric acid promotes urinary stones.
  • To highlight the importance of managing hyperuricosuria for stone prevention.

Summary:

  • Hyperuricosuria, present in about 23% of clinical urolithiasis cases, frequently results in calcium oxalate stones (75%) and uric acid stones (25%).
  • Uric acid not only forms stones but also actively promotes calcium oxalate stone development.

Related Experiment Videos

  • Previous research demonstrated allopurinol's preventive effect on recurrent calcium oxalate stone formers, suggesting hyperuricosuria promotes stone formation or inhibits natural stone inhibitors.

    • Impact:

    • Emphasizes the clinical significance of treating hyperuricosuria to prevent urinary stone recurrence.
    • Provides insights into the dual role of uric acid in stone pathogenesis.
    • Supports therapeutic strategies targeting hyperuricosuria for effective urolithiasis management.