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In vivo evaluation of corneal endothelial function following cataract surgery
1Department of Ophthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Background And Objective:
To quantify corneal endothelial function measured in vivo following extracapsular cataract extraction (ECCE) and posterior chamber intraocular lens (PC IOL) implantation.
Patients And Methods:
Endothelial function was assessed in 18 patients using recovery of the corneal hydration rate following induced cornea swelling before and after ECCE and PC IOL implantation.
Results:
The mean percentage recovery per hour (PRPH) showed a significant decrease at 12 and 24 weeks after surgery compared with before surgery (P < .01). A decrease in PRPH of more than 5% was observed in 55.6% and 66.7% of the eyes at 12 and 24 weeks after surgery, respectively.
Conclusions:
PRPH measured in vivo demonstrates decreased endothelial function following ECCE and PC IOL implantation. The PRPH measures even slight changes in endothelial function and could be useful in evaluating endothelial damage.