Related Experiment Videos
Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. II. Loci on the second and third
N Perrimon1, A Lanjuin, C Arnold
1Department of Genetics, Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts 02115, USA. perrimon@rascal.med.harvard.edu
Genetics
|December 1, 1996
Abstract:
Screens for zygotic lethal mutations that are associated with specific maternal effect lethal phenotypes have only been conducted for the X chromosome. To identify loci on the autosomes, which represent four-fifths of the Drosophila genome, we have used the autosomal "FLP-DFS" technique to screen a collection of 496 P element-induced mutations established by the Berkeley Drosophila Genome Project. We have identified 64 new loci whose gene products are required for proper egg formation or normal embryonic development.